{"id":3747,"date":"2025-09-08T01:23:56","date_gmt":"2025-09-07T21:53:56","guid":{"rendered":"https:\/\/factnamesalamat.ir\/?p=3747"},"modified":"2025-09-08T01:23:56","modified_gmt":"2025-09-07T21:53:56","slug":"%d9%85%d9%84%d8%a7%d8%aa%d9%88%d9%86%db%8c%d9%86","status":"publish","type":"post","link":"https:\/\/factnamesalamat.ir\/?p=3747","title":{"rendered":"\u0631\u0627\u0633\u062a\u06cc\u200c\u0622\u0632\u0645\u0627\u06cc\u06cc: \u0645\u0644\u0627\u062a\u0648\u0646\u06cc\u0646 \u062f\u0631 \u062f\u0631\u0645\u0627\u0646 \u0633\u0631\u0637\u0627\u0646 \u0645\u0624\u062b\u0631 \u0627\u0633\u062a."},"content":{"rendered":"<p><span style=\"color: #993300;\"><strong>\u0628\u06cc\u0627\u0646 \u0645\u0633\u0626\u0644\u0647<\/strong><\/span><\/p>\n<p>\u06af\u0627\u0647\u06cc \u0627\u06cc\u0646 \u067e\u0631\u0633\u0634 \u0645\u0637\u0631\u062d \u0645\u06cc\u200c\u0634\u0648\u062f \u06a9\u0647 \u0645\u0635\u0631\u0641 \u0645\u06a9\u0645\u0644 \u0645\u0644\u0627\u062a\u0648\u0646\u06cc\u0646 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\u0628\u0647 \u0633\u0631\u0637\u0627\u0646\u060c \u0645\u062f\u06cc\u0631\u06cc\u062a \u0632\u06cc\u0633\u062a\u200c\u0640\u200c\u0631\u0648\u0627\u0646\u06cc \u0648 \u062f\u0627\u0631\u0648\u06cc\u06cc \u0627\u062e\u062a\u0644\u0627\u0644\u0627\u062a \u062e\u0648\u0627\u0628 \u0631\u0627 \u0645\u0637\u0631\u062d \u0645\u06cc\u200c\u06a9\u0646\u062f\u061b \u0645\u0644\u0627\u062a\u0648\u0646\u06cc\u0646 \u0635\u0631\u0641\u0627\u064b \u0628\u0647\u200c\u0639\u0646\u0648\u0627\u0646 \u06cc\u06a9 \u06af\u0632\u06cc\u0646\u0647 \u0628\u0631\u0627\u06cc <\/span><strong style=\"font-size: 9pt;\">\u0628\u06cc\u200c\u062e\u0648\u0627\u0628\u06cc<\/strong><span style=\"font-size: 9pt;\"> \u0645\u0637\u0631\u062d \u0627\u0633\u062a \u0648 \u0646\u0647 \u062f\u0631\u0645\u0627\u0646 \u0633\u0631\u0637\u0627\u0646. \u0647\u0645\u200c\u0686\u0646\u06cc\u0646 \u062f\u0631 \u062d\u0648\u0632\u0647 \u062e\u0633\u062a\u06af\u06cc \u0645\u0631\u062a\u0628\u0637 \u0628\u0627 \u0633\u0631\u0637\u0627\u0646\u060c \u0628\u0647\u200c\u0631\u0648\u0632\u200c\u0631\u0633\u0627\u0646\u06cc \u0645\u0634\u062a\u0631\u06a9 SIO\u2013ASCO\u060c \u0627\u0633\u062a\u0641\u0627\u062f\u0647 \u0627\u0632 \u0645\u062f\u0627\u062e\u0644\u0627\u062a \u063a\u06cc\u0631\u062f\u0627\u0631\u0648\u06cc\u06cc (\u0648\u0631\u0632\u0634\u060c CBT\u060c \u0630\u0647\u0646\u200c\u0622\u06af\u0627\u0647\u06cc \u0648\u2026) \u0631\u0627 \u062a\u0648\u0635\u06cc\u0647 \u0645\u06cc\u200c\u06a9\u0646\u062f \u0648 \u0628\u0631\u0627\u06cc \u0645\u0644\u0627\u062a\u0648\u0646\u06cc\u0646\u060c <\/span><strong style=\"font-size: 9pt;\">\u062a\u0648\u0635\u06cc\u0647\u200c\u0627\u06cc \u0631\u0627 \u0628\u0647 \u0646\u0641\u0639 \u062a\u0627\u062b\u06cc\u0631 \u0622\u0646 \u0628\u0631 \u062e\u0633\u062a\u06af\u06cc \u06cc\u0627 \u0628\u0642\u0627\u0621<\/strong><span style=\"font-size: 9pt;\"> \u0627\u0631\u0627\u0626\u0647 \u0646\u0645\u06cc\u200c\u062f\u0647\u062f. \u0628\u0647 \u0628\u06cc\u0627\u0646 \u0631\u0648\u0634\u0646\u060c \u062f\u0631 \u062f\u0633\u062a\u0648\u0631\u0627\u0644\u0639\u0645\u0644\u200c\u0647\u0627\u06cc \u0628\u0627\u0644\u06cc\u0646\u06cc \u0645\u0639\u062a\u0628\u0631\u060c \u0645\u0644\u0627\u062a\u0648\u0646\u06cc\u0646 \u0646\u0642\u0634 \u0636\u062f\u0645\u0627\u0644\u06cc\u06af\u0646\u0646\u062a \u0627\u062b\u0628\u0627\u062a\u200c\u0634\u062f\u0647 \u0646\u062f\u0627\u0631\u062f <\/span><span style=\"font-size: 9pt;\">(\u06f4\u060c \u06f5<\/span><span style=\"font-size: 9pt;\">).<\/span><\/p>\n<p><strong>\u00a0<\/strong><strong>\u06a9\u0627\u0631\u0622\u0632\u0645\u0627\u06cc\u06cc\u200c\u0647\u0627\u06cc \u0628\u0627\u0644\u06cc\u0646\u06cc \u0642\u062f\u06cc\u0645\u06cc \u0628\u0627 \u0627\u062f\u0639\u0627\u06cc \u0627\u062b\u0631 \u0628\u0631 \u0628\u0642\u0627\u0621: \u0686\u0631\u0627 \u0642\u0627\u0646\u0639\u200c\u06a9\u0646\u0646\u062f\u0647 \u0645\u062d\u0633\u0648\u0628 \u0646\u0645\u06cc\u200c\u0634\u0648\u0646\u062f\u061f<\/strong><\/p>\n<p>\u0628\u0631\u062e\u06cc<span style=\"font-size: 9pt;\">\u00a0<\/span><span style=\"font-size: 9pt;\">\u06a9\u0627\u0631\u0622\u0632\u0645\u0627\u06cc\u06cc\u200c\u0647\u0627\u06cc \u06a9\u0648\u0686\u06a9 \u06a9\u0647 \u0646\u062a\u0627\u06cc\u062c\u06cc \u0631\u0627 \u0628\u0647 \u0646\u0641\u0639 \u0645\u0644\u0627\u062a\u0648\u0646\u06cc\u0646 \u062f\u0631 \u0645\u0648\u0631\u062f<\/span><span style=\"font-size: 9pt;\"> \u00ab\u06a9\u0627\u0647\u0634 \u0645\u0631\u06af\u200c\u0648\u0645\u06cc\u0631\/\u0627\u0641\u0632\u0627\u06cc\u0634 \u067e\u0627\u0633\u062e \u062a\u0648\u0645\u0648\u0631\u06cc\u00bb \u0645\u0646\u062a\u0634\u0631 \u06a9\u0631\u062f\u0646\u062f\u060c \u063a\u0627\u0644\u0628\u0627\u064b \u062a\u06a9\u200c\u0645\u0631\u06a9\u0632\u06cc \u0628\u0648\u062f\u0647 \u0648 \u06af\u0627\u0647\u06cc \u0628\u0647\u200c\u0639\u0644\u062a \u0645\u062d\u062f\u0648\u062f\u06cc\u062a\u200c\u0647\u0627\u06cc\u06cc \u0645\u0627\u0646\u0646\u062f \u062d\u062c\u0645 \u0646\u0645\u0648\u0646\u0647 \u0627\u0646\u062f\u06a9\u060c \u06a9\u0648\u0631\u0633\u0627\u0632\u06cc \u0646\u0627\u06a9\u0627\u0641\u06cc \u0648 \u06af\u0632\u0627\u0631\u0634\u200c\u062f\u0647\u06cc \u0646\u0627\u0642\u0635\u060c \u062e\u0637\u0631 \u0633\u0648\u06af\u06cc\u0631\u06cc (bias) \u0628\u0627\u0644\u0627\u06cc\u06cc \u062f\u0627\u0631\u0646\u062f. \u0645\u0646\u0627\u0628\u0639 \u0645\u0639\u062a\u0628\u0631 \u0645\u0627\u0646\u0646\u062f \u067e\u0627\u06cc\u06af\u0627\u0647\u200c\u0647\u0627\u06cc PDQ\/NCI \u0628\u0627\u0631\u0647\u0627 \u062a\u0623\u06a9\u06cc\u062f \u06a9\u0631\u062f\u0647\u200c\u0627\u0646\u062f \u06a9\u0647 \u0628\u0631\u0627\u06cc \u0627\u062b\u0628\u0627\u062a \u0686\u0646\u06cc\u0646 \u0627\u062f\u0639\u0627\u0647\u0627\u06cc\u06cc \u0628\u0647 \u0627\u0646\u062c\u0627\u0645 <\/span><strong style=\"font-size: 9pt;\">\u06a9\u0627\u0631\u0622\u0632\u0645\u0627\u06cc\u06cc\u200c\u0647\u0627\u06cc \u062a\u0635\u0627\u062f\u0641\u06cc\u200c\u0633\u0627\u0632\u06cc\u200c\u0634\u062f\u0647\u060c \u0686\u0646\u062f\u0645\u0631\u06a9\u0632\u06cc \u0648 \u06a9\u0648\u0631\u0633\u0627\u0632\u06cc\u200c\u0634\u062f\u0647<\/strong><span style=\"font-size: 9pt;\"> \u0646\u06cc\u0627\u0632 \u0627\u0633\u062a\u060c \u0686\u06cc\u0632\u06cc \u06a9\u0647 \u0647\u0646\u0648\u0632 \u0628\u0631\u0627\u06cc \u0646\u062a\u06cc\u062c\u0647\u200c\u06af\u06cc\u0631\u06cc \u062f\u0631\u0628\u0627\u0631\u0647 \u00ab\u0627\u062b\u0631 \u062f\u0631\u0645\u0627\u0646\u06cc \u0628\u0631 \u062e\u0648\u062f \u0633\u0631\u0637\u0627\u0646\u00bb \u0648\u062c\u0648\u062f \u0646\u062f\u0627\u0631\u062f <\/span><span style=\"font-size: 9pt;\">(\u06f2\u060c \u06f1\u06f0<\/span><span style=\"font-size: 9pt;\">).<\/span><\/p>\n<p><strong>\u00a0<\/strong><strong>\u0634\u0648\u0627\u0647\u062f \u0645\u0648\u062c\u0648\u062f \u0628\u06cc\u0634\u062a\u0631 \u0628\u0647 \u06a9\u0646\u062a\u0631\u0644 \u0639\u0644\u0627\u0626\u0645 (\u0645\u062b\u0644 \u062e\u0648\u0627\u0628) \u0627\u0634\u0627\u0631\u0647 \u062f\u0627\u0631\u0646\u062f \u062a\u0627 \u0627\u062b\u0631 \u0636\u062f\u0651\u062a\u0648\u0645\u0648\u0631<\/strong><\/p>\n<p>\u062f\u0631 \u0628\u06cc\u0645\u0627\u0631\u0627\u0646 \u0633\u0631\u0637\u0627\u0646\u06cc\u060c \u0645\u0644\u0627\u062a\u0648\u0646\u06cc\u0646 \u0645\u06cc\u200c\u062a\u0648\u0627\u0646\u062f \u0628\u0647 \u0628\u0647\u0628\u0648\u062f\u06cc \u062f\u0631 \u0628\u0631\u062e\u06cc \u0634\u0627\u062e\u0635\u200c\u0647\u0627\u06cc \u062e\u0648\u0627\u0628 \u06a9\u0645\u06a9 \u06a9\u0646\u062f\u060c \u0648\u0644\u06cc \u0628\u0647\u0628\u0648\u062f\u06cc \u062f\u0631 \u067e\u06cc\u0627\u0645\u062f\u0647\u0627\u06cc \u0633\u062e\u062a (\u0645\u0627\u0646\u0646\u062f \u0628\u0642\u0627\u06cc \u06a9\u0644\u06cc\u060c \u0628\u0642\u0627\u06cc \u0628\u062f\u0648\u0646 \u067e\u06cc\u0634\u0631\u0641\u062a \u06cc\u0627 \u06a9\u0648\u0686\u06a9\u200c\u0634\u062f\u0646 \u062a\u0648\u0645\u0648\u0631) \u0646\u0634\u0627\u0646 \u062f\u0627\u062f\u0647 \u0646\u0634\u062f\u0647 \u0627\u0633\u062a. \u062d\u062a\u06cc \u062f\u0631 \u062d\u0648\u0632\u0647 \u062e\u0633\u062a\u06af\u06cc\u060c \u062f\u0633\u062a\u0648\u0631\u0627\u0644\u0639\u0645\u0644\u200c\u0647\u0627 \u0628\u0631 \u0645\u062f\u0627\u062e\u0644\u0627\u062a \u063a\u06cc\u0631\u062f\u0627\u0631\u0648\u06cc\u06cc \u062a\u0623\u06a9\u06cc\u062f \u062f\u0627\u0631\u0646\u062f \u0648 \u0634\u0648\u0627\u0647\u062f \u062f\u0627\u0631\u0648\u06cc\u06cc \u0628\u0631\u0627\u06cc \u0645\u0644\u0627\u062a\u0648\u0646\u06cc\u0646 \u0642\u0648\u06cc \u0646\u06cc\u0633\u062a. \u0628\u0646\u0627\u0628\u0631\u0627\u06cc\u0646 \u0627\u06af\u0631 \u0628\u06cc\u0645\u0627\u0631 \u0627\u0632 \u0645\u0644\u0627\u062a\u0648\u0646\u06cc\u0646 \u0633\u0648\u062f\u06cc \u0628\u0628\u06cc\u0646\u062f\u060c \u0645\u062d\u062a\u0645\u0644\u200c\u062a\u0631 \u0627\u0633\u062a \u06a9\u0647 \u062f\u0631 <strong>\u0639\u0644\u0627\u0626\u0645<\/strong> (\u062e\u0648\u0627\u0628\/\u06a9\u06cc\u0641\u06cc\u062a \u0632\u0646\u062f\u06af\u06cc) \u0628\u0627\u0634\u062f\u060c \u0646\u0647 \u062f\u0631 <strong>\u0631\u06cc\u0634\u0647 \u0628\u06cc\u0645\u0627\u0631\u06cc <\/strong>(\u06f5\u2013\u06f7).<\/p>\n<p><strong>\u00a0<\/strong><strong>\u062f\u0648\u0632\u0647\u0627 \u0648 \u0628\u06cc\u200c\u062e\u0637\u0631 \u0628\u0648\u062f\u0646: \u0647\u0631 \u00ab\u0637\u0628\u06cc\u0639\u06cc\u00bb\u0627\u06cc \u0628\u06cc\u200c\u062e\u0637\u0631 \u0646\u06cc\u0633\u062a<\/strong><\/p>\n<p>\u062f\u0631 \u06a9\u0627\u0631\u0622\u0632\u0645\u0627\u06cc\u06cc\u200c\u0647\u0627\u060c \u062f\u0648\u0632\u0647\u0627\u06cc \u0645\u062a\u0646\u0648\u0639\u06cc (\u06af\u0627\u0647\u06cc \u06f2 \u062a\u0627 \u06f2\u06f0 \u0645\u06cc\u0644\u06cc\u200c\u06af\u0631\u0645 \u0634\u0628\u0627\u0646\u0647) \u0628\u0647\u200c\u06a9\u0627\u0631 \u0631\u0641\u062a\u0647\u060c \u0627\u0645\u0627 \u0627\u0633\u062a\u0627\u0646\u062f\u0627\u0631\u062f \u0648\u0627\u062d\u062f\u06cc \u0628\u0631\u0627\u06cc \u0628\u06cc\u0645\u0627\u0631\u0627\u0646 \u0633\u0631\u0637\u0627\u0646\u06cc \u0648\u062c\u0648\u062f \u0646\u062f\u0627\u0631\u062f \u0648 \u06a9\u06cc\u0641\u06cc\u062a \u0645\u062d\u0635\u0648\u0644\u0627\u062a \u0628\u0627\u0632\u0627\u0631 \u0622\u0632\u0627\u062f \u0645\u062a\u0641\u0627\u0648\u062a \u0627\u0633\u062a. \u0645\u0646\u0627\u0628\u0639 \u0645\u0639\u062a\u0628\u0631 \u0627\u0646\u06a9\u0648\u0644\u0648\u0698\u06cc (NCI\/PDQ) \u0648 \u0645\u0631\u0627\u06a9\u0632 \u0622\u06a9\u0627\u062f\u0645\u06cc\u06a9 (Memorial Sloan Kettering) \u06cc\u0627\u062f\u0622\u0648\u0631\u06cc \u0645\u06cc\u200c\u06a9\u0646\u0646\u062f \u06a9\u0647 \u0645\u0644\u0627\u062a\u0648\u0646\u06cc\u0646 \u0645\u06cc\u200c\u062a\u0648\u0627\u0646\u062f \u0628\u0627 \u062f\u0627\u0631\u0648\u0647\u0627 (\u0628\u0647\u200c\u0648\u06cc\u0698\u0647 \u062f\u0627\u0631\u0648\u0647\u0627\u06cc \u0645\u062a\u0627\u0628\u0648\u0644\u06cc\u0632\u0647\u200c\u0634\u0648\u0646\u062f\u0647 \u0627\u0632 \u0645\u0633\u06cc\u0631\u0647\u0627\u06cc CYP \u0648 \u062f\u0627\u0631\u0648\u0647\u0627\u06cc \u062e\u0648\u0627\u0628\u200c\u0622\u0648\u0631\/\u0622\u0631\u0627\u0645\u200c\u0628\u062e\u0634) \u062a\u062f\u0627\u062e\u0644 \u06a9\u0646\u062f \u0648 \u0628\u0627\u0639\u062b \u062e\u0648\u0627\u0628\u200c\u0622\u0644\u0648\u062f\u06af\u06cc \u0631\u0648\u0632\u0627\u0646\u0647\u060c \u0633\u0631\u06af\u06cc\u062c\u0647 \u0648\u2026 \u0634\u0648\u062f\u061b \u062f\u0631 \u0627\u062e\u062a\u0644\u0627\u0644\u0627\u062a \u062e\u0648\u062f\u0627\u06cc\u0645\u0646\u06cc \u0648 \u0628\u0627\u0631\u062f\u0627\u0631\u06cc \u0646\u06cc\u0632 \u0627\u062d\u062a\u06cc\u0627\u0637 \u062f\u0631 \u0645\u0635\u0631\u0641 \u0622\u0646 \u062a\u0648\u0635\u06cc\u0647 \u0645\u06cc\u200c\u0634\u0648\u062f (\u06f2\u060c \u06f9).<\/p>\n<p><strong>\u00a0<\/strong><strong>\u062c\u0645\u0639\u200c\u0628\u0646\u062f\u06cc \u0634\u0648\u0627\u0647\u062f \u0628\u0627\u0644\u06cc\u0646\u06cc \u0627\u0645\u0631\u0648\u0632: \u062f\u0631\u0645\u0627\u0646 \u0633\u0631\u0637\u0627\u0646\u061f \u062e\u06cc\u0631\u061b \u06a9\u0645\u06a9\u0650 \u0639\u0644\u0627\u0626\u0645\u06cc\u061f \u0634\u0627\u06cc\u062f<\/strong><\/p>\n<p>\u0633\u0637\u0631 \u0628\u0647 \u0633\u0637\u0631 \u062f\u0627\u062f\u0647\u200c\u0647\u0627 \u0646\u0634\u0627\u0646 \u0645\u06cc\u200c\u062f\u0647\u062f \u06a9\u0647 \u0645\u0644\u0627\u062a\u0648\u0646\u06cc\u0646 \u0647\u0646\u0648\u0632 <strong>\u0628\u0647\u200c\u0639\u0646\u0648\u0627\u0646 \u062f\u0631\u0645\u0627\u0646 \u0636\u062f\u0651\u0633\u0631\u0637\u0627\u0646<\/strong><strong> (Disease-Modifying)<\/strong> \u062c\u0627\u06cc\u06af\u0627\u0647\u06cc \u0646\u062f\u0627\u0631\u062f. \u0645\u0631\u0648\u0631\u0647\u0627\u06cc \u0646\u0638\u0627\u0645\u200c\u0645\u0646\u062f \u0648 \u062f\u0633\u062a\u0648\u0631\u0627\u0644\u0639\u0645\u0644\u200c\u0647\u0627\u06cc \u0628\u0627\u0644\u06cc\u0646\u06cc \u062a\u0645\u0631\u06a9\u0632 \u0627\u0633\u062a\u0641\u0627\u062f\u0647 \u0631\u0627 \u0628\u0631 <strong>\u0645\u062f\u06cc\u0631\u06cc\u062a \u0639\u0644\u0627\u0626\u0645<\/strong> (\u0628\u06cc\u0634\u062a\u0631 \u062e\u0648\u0627\u0628) \u0645\u06cc\u200c\u06af\u0630\u0627\u0631\u0646\u062f \u0648 \u0628\u0631\u0627\u06cc \u067e\u06cc\u0627\u0645\u062f\u0647\u0627\u06cc \u062d\u06cc\u0627\u062a\u06cc \u0633\u0631\u0637\u0627\u0646 (\u0628\u0642\u0627\u0621\/\u06a9\u0646\u062a\u0631\u0644 \u062a\u0648\u0645\u0648\u0631) \u0634\u0648\u0627\u0647\u062f \u0631\u0627 \u0646\u0627\u06a9\u0627\u0641\u06cc \u0645\u06cc\u200c\u062f\u0627\u0646\u0646\u062f. \u0647\u0631\u06af\u0648\u0646\u0647 \u0627\u0633\u062a\u0641\u0627\u062f\u0647 \u0628\u0627\u06cc\u062f \u0634\u062e\u0635\u06cc\u200c\u0633\u0627\u0632\u06cc\u200c\u0634\u062f\u0647\u060c \u0628\u0627 \u0646\u0638\u0631 \u0627\u0646\u06a9\u0648\u0644\u0648\u0698\u06cc\u0633\u062a \u0648 \u0628\u0627 \u067e\u0627\u06cc\u0634 \u062a\u062f\u0627\u062e\u0644\u0627\u062a \u062f\u0627\u0631\u0648\u06cc\u06cc \u0628\u0627\u0634\u062f (\u06f5\u060c \u06f7).<\/p>\n<p>&nbsp;<\/p>\n<blockquote>\n<p style=\"text-align: center;\"><a title=\"\u0686\u0647 \u0639\u0648\u0627\u0645\u0644 \u0645\u0648\u062b\u0631\u06cc \u062f\u0631 \u0628\u0627\u0632\u06af\u0634\u062a \u0628\u0647 \u06a9\u0627\u0631 \u062f\u0631 \u0632\u0646\u0627\u0646 \u0645\u0628\u062a\u0644\u0627 \u0628\u0647 \u0633\u0631\u0637\u0627\u0646 \u067e\u0633\u062a\u0627\u0646 \u0648\u062c\u0648\u062f \u062f\u0627\u0631\u0646\u062f\u061f\" href=\"https:\/\/factnamesalamat.ir\/?p=3416\">\u0686\u0647 \u0639\u0648\u0627\u0645\u0644 \u0645\u0648\u062b\u0631\u06cc \u062f\u0631 \u0628\u0627\u0632\u06af\u0634\u062a \u0628\u0647 \u06a9\u0627\u0631 \u062f\u0631 \u0632\u0646\u0627\u0646 \u0645\u0628\u062a\u0644\u0627 \u0628\u0647 \u0633\u0631\u0637\u0627\u0646 \u067e\u0633\u062a\u0627\u0646 \u0648\u062c\u0648\u062f \u062f\u0627\u0631\u0646\u062f\u061f<\/a><\/p>\n<\/blockquote>\n<p>&nbsp;<\/p>\n<p><span style=\"color: #993300;\"><strong>\u0646\u062a\u06cc\u062c\u0647\u200c\u06af\u06cc\u0631\u06cc<\/strong><\/span><\/p>\n<p>\u0628\u0627 \u062a\u06a9\u06cc\u0647 \u0628\u0631 \u0645\u0631\u0648\u0631\u0647\u0627\u06cc \u0646\u0638\u0627\u0645\u200c\u0645\u0646\u062f \u0628\u0647\u200c\u0631\u0648\u0632\u0634\u062f\u0647\u060c \u062f\u0633\u062a\u0648\u0631\u0627\u0644\u0639\u0645\u0644\u200c\u0647\u0627\u06cc \u0628\u0627\u0644\u06cc\u0646\u06cc ASCO\/SIO \u0648 ESMO \u0648 \u0645\u0646\u0627\u0628\u0639 \u0645\u0639\u062a\u0628\u0631 \u0627\u0646\u06a9\u0648\u0644\u0648\u0698\u06cc\u060c <strong>\u0627\u062f\u0639\u0627\u06cc \u00ab\u0645\u0644\u0627\u062a\u0648\u0646\u06cc\u0646 \u062f\u0631 \u062f\u0631\u0645\u0627\u0646 \u0633\u0631\u0637\u0627\u0646 \u0645\u0624\u062b\u0631 \u0627\u0633\u062a\u00bb \u0646\u0627\u062f\u0631\u0633\u062a\/\u062a\u0623\u06cc\u06cc\u062f\u0646\u0634\u062f\u0647 \u0627\u0633\u062a<\/strong>. \u0645\u0644\u0627\u062a\u0648\u0646\u06cc\u0646 \u0645\u0645\u06a9\u0646 \u0627\u0633\u062a \u0628\u0631\u0627\u06cc \u0628\u0647\u0628\u0648\u062f\u06cc \u062f\u0631 \u0628\u0631\u062e\u06cc <strong>\u0639\u0644\u0627\u0626\u0645<\/strong> (\u0628\u0647\u200c\u0648\u06cc\u0698\u0647 \u0645\u0634\u06a9\u0644\u0627\u062a \u062e\u0648\u0627\u0628) \u0633\u0648\u062f\u0645\u0646\u062f \u0628\u0627\u0634\u062f\u060c \u0627\u0645\u0627 \u0634\u0648\u0627\u0647\u062f \u0645\u0639\u062a\u0628\u0631\u06cc \u0627\u0632 \u0622\u0646 \u0628\u0631\u0627\u06cc <strong>\u0627\u062b\u0631 \u0645\u0633\u062a\u0642\u06cc\u0645 \u0636\u062f\u0651\u062a\u0648\u0645\u0648\u0631 \u06cc\u0627 \u0628\u0647\u0628\u0648\u062f \u0628\u0642\u0627\u0621<\/strong> \u0648\u062c\u0648\u062f \u0646\u062f\u0627\u0631\u062f. \u0628\u0646\u0627\u0628\u0631\u0627\u06cc\u0646 \u0645\u0644\u0627\u062a\u0648\u0646\u06cc\u0646 \u062f\u0631 \u0628\u0647\u062a\u0631\u06cc\u0646 \u062d\u0627\u0644\u062a\u060c \u06cc\u06a9 <strong>\u06af\u0632\u06cc\u0646\u0647 \u06a9\u0645\u06a9\u06cc\u0650 \u0639\u0644\u0627\u0626\u0645\u06cc<\/strong> \u0628\u0627 \u0634\u0648\u0627\u0647\u062f \u0645\u062d\u062f\u0648\u062f \u0627\u0633\u062a\u060c \u0646\u0647 \u062f\u0631\u0645\u0627\u0646 \u0633\u0631\u0637\u0627\u0646. \u0627\u0633\u062a\u0641\u0627\u062f\u0647 \u0628\u06cc\u200c\u0628\u0631\u0646\u0627\u0645\u0647\u060c \u0628\u0647\u200c\u062e\u0635\u0648\u0635 \u0628\u062f\u0648\u0646 \u0627\u0637\u0644\u0627\u0639 \u062a\u06cc\u0645 \u062f\u0631\u0645\u0627\u0646\u060c \u062a\u0648\u0635\u06cc\u0647 \u0646\u0645\u06cc\u200c\u0634\u0648\u062f.<\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"color: #993300;\"><strong>\u0645\u0646\u0627\u0628\u0639<\/strong><\/span><\/p>\n<p dir=\"ltr\">\u06f1- World Health Organization (WHO). Cancer \u2013 Key facts. Updated 2024. Available from WHO fact sheet (\u062f\u0631\u0645\u0627\u0646\u200c\u0647\u0627\u06cc \u0627\u0633\u062a\u0627\u0646\u062f\u0627\u0631\u062f: \u062c\u0631\u0627\u062d\u06cc\u060c \u0631\u0627\u062f\u06cc\u0648\u062a\u0631\u0627\u067e\u06cc\u060c \u0634\u06cc\u0645\u06cc\u200c\u062f\u0631\u0645\u0627\u0646\u06cc\u060c \u0627\u06cc\u0645\u0646\u06cc\u200c\u062f\u0631\u0645\u0627\u0646\u06cc). (<a href=\"https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/cancer?utm_source=chatgpt.com\">World Health Organization<\/a>)<\/p>\n<p dir=\"ltr\">2- National Cancer Institute (NCI), PDQ\u00ae. Sleep Disorders\u2014Health Professional Version. Updated Jul 17, 2024. (\u0628\u06cc\u0627\u0646 \u0646\u0642\u0634 \u0645\u0644\u0627\u062a\u0648\u0646\u06cc\u0646 \u062f\u0631 \u062e\u0648\u0627\u0628 \u0648 \u0636\u0631\u0648\u0631\u062a \u06a9\u0627\u0631\u0622\u0632\u0645\u0627\u06cc\u06cc\u200c\u0647\u0627\u06cc \u0628\u0627\u06a9\u06cc\u0641\u06cc\u062a \u0628\u0631\u0627\u06cc \u0627\u062f\u0639\u0627\u0647\u0627\u06cc \u062f\u0631\u0645\u0627\u0646\u06cc). (<a href=\"https:\/\/www.cancer.gov\/about-cancer\/treatment\/side-effects\/sleep-disorders-hp-pdq?utm_source=chatgpt.com\">Cancer.gov<\/a>)<\/p>\n<p dir=\"ltr\">3- Gong Y-Q, et al. The mechanisms and roles of melatonin in gastrointestinal cancers. <em>Frontiers in Oncology.<\/em> 2022. (\u0645\u0631\u0648\u0631 \u0645\u06a9\u0627\u0646\u06cc\u06a9\u06cc\u061b \u0645\u0633\u06cc\u0631\u0647\u0627\u06cc \u0622\u067e\u0648\u067e\u062a\u0648\u0632\/\u0622\u0646\u0698\u06cc\u0648\u0698\u0646\u0632\/\u0627\u06cc\u0645\u0646\u06cc). (<a href=\"https:\/\/www.frontiersin.org\/journals\/oncology\/articles\/10.3389\/fonc.2022.1066698\/full?utm_source=chatgpt.com\">Frontiers<\/a>)<\/p>\n<p dir=\"ltr\">4- Rodr\u00edguez-Santana C, et al. Role of Melatonin in Cancer: Effect on Clock Genes. <em>International Journal of Molecular Sciences.<\/em> 2023. (\u0646\u0642\u0634 \u0633\u0627\u0639\u062a \u0632\u06cc\u0633\u062a\u06cc \u0648 \u0645\u0644\u0627\u062a\u0648\u0646\u06cc\u0646 \u062f\u0631 \u0633\u0631\u0637\u0627\u0646). (<a href=\"https:\/\/www.mdpi.com\/1422-0067\/24\/3\/1919?utm_source=chatgpt.com\">MDPI<\/a>)<\/p>\n<p dir=\"ltr\">5- Cochrane Review (2025). Melatonin for adults with cancer: effects on sleep, fatigue, nausea, and quality of life. (\u062a\u0645\u0631\u06a9\u0632 \u0628\u0631 \u0639\u0644\u0627\u0626\u0645\u061b \u0646\u0627\u06a9\u0627\u0641\u06cc \u0628\u0648\u062f\u0646 \u0634\u0648\u0627\u0647\u062f \u0628\u0631\u0627\u06cc \u067e\u06cc\u0627\u0645\u062f\u0647\u0627\u06cc \u0633\u062e\u062a\u0650 \u0633\u0631\u0637\u0627\u0646). (<a href=\"https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/cancer?utm_source=chatgpt.com\">World Health Organization<\/a>)<\/p>\n<p dir=\"ltr\">6- European Society for Medical Oncology (ESMO). Clinical Practice Guideline on Insomnia in Patients with Cancer (2023). (\u0645\u0644\u0627\u062a\u0648\u0646\u06cc\u0646 \u0628\u0647\u200c\u0639\u0646\u0648\u0627\u0646 \u06af\u0632\u06cc\u0646\u0647\u0654 \u0628\u06cc\u200c\u062e\u0648\u0627\u0628\u06cc\u061b \u0646\u0647 \u062f\u0631\u0645\u0627\u0646 \u0636\u062f\u0651\u0633\u0631\u0637\u0627\u0646). (<a href=\"https:\/\/www.who.int\/europe\/news-room\/fact-sheets\/item\/cancer-treatment?utm_source=chatgpt.com\">World Health Organization<\/a>)<\/p>\n<p dir=\"ltr\">7- ASCO\u2013Society for Integrative Oncology (SIO). Management of Fatigue in Adult Survivors of Cancer\u2014Guideline Update (2024). (\u062a\u0623\u06a9\u06cc\u062f \u0628\u0631 \u0645\u062f\u0627\u062e\u0644\u0627\u062a \u063a\u06cc\u0631\u062f\u0627\u0631\u0648\u06cc\u06cc\u061b \u0639\u062f\u0645 \u062a\u0648\u0635\u06cc\u0647 \u0634\u0648\u0627\u0647\u062f \u0642\u0648\u06cc \u0628\u0631\u0627\u06cc \u0645\u0644\u0627\u062a\u0648\u0646\u06cc\u0646 \u062f\u0631 \u062e\u0633\u062a\u06af\u06cc\/\u067e\u06cc\u0627\u0645\u062f\u0647\u0627\u06cc \u0633\u062e\u062a). (<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC12082589\/?utm_source=chatgpt.com\">PMC<\/a>, <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38754041\/?utm_source=chatgpt.com\">PubMed<\/a>)<\/p>\n<p dir=\"ltr\">8- Memorial Sloan Kettering Cancer Center. About Herbs\u2014Melatonin Monograph. (\u0627\u06cc\u0645\u0646\u06cc\u060c \u062a\u062f\u0627\u062e\u0644\u0627\u062a \u062f\u0627\u0631\u0648\u06cc\u06cc\u060c \u0627\u062d\u062a\u06cc\u0627\u0637\u0627\u062a).<\/p>\n<p dir=\"ltr\">\u06f9- Centers for Disease Control and Prevention (CDC). MMWR (2022): Pediatric Melatonin Ingestions\u2014United States, 2012\u2013\u06f2\u06f0\u06f2\u06f1. (\u0627\u0641\u0632\u0627\u06cc\u0634 \u0645\u0633\u0645\u0648\u0645\u06cc\u062a\u200c\u0647\u0627\u061b \u0647\u0634\u062f\u0627\u0631 \u0627\u06cc\u0645\u0646\u06cc \u0648 \u06a9\u06cc\u0641\u06cc\u062a \u0641\u0631\u0622\u0648\u0631\u062f\u0647\u200c\u0647\u0627).<\/p>\n<p dir=\"ltr\">\u06f1\u06f0- Alshehri FS, et al. A review of the potential use of melatonin in cancer treatment. 2024 (ClinicalTrials.gov-based review\u061b \u0646\u06cc\u0627\u0632 \u0628\u0647 RCT\u0647\u0627\u06cc \u0628\u0627\u06a9\u06cc\u0641\u06cc\u062a \u0648 \u0645\u062d\u062f\u0648\u062f\u06cc\u062a \u0634\u0648\u0627\u0647\u062f \u0628\u0627\u0644\u06cc\u0646\u06cc \u0645\u0633\u062a\u0642\u06cc\u0645). (<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC11557022\/?utm_source=chatgpt.com\">PMC<\/a>)<\/p>\n<p dir=\"ltr\">\n","protected":false},"excerpt":{"rendered":"<p>\u0628\u06cc\u0627\u0646 \u0645\u0633\u0626\u0644\u0647 \u06af\u0627\u0647\u06cc \u0627\u06cc\u0646 \u067e\u0631\u0633\u0634 \u0645\u0637\u0631\u062d \u0645\u06cc\u200c\u0634\u0648\u062f \u06a9\u0647 \u0645\u0635\u0631\u0641 \u0645\u06a9\u0645\u0644 \u0645\u0644\u0627\u062a\u0648\u0646\u06cc\u0646 (\u0647\u0648\u0631\u0645\u0648\u0646\u06cc \u06a9\u0647 \u0628\u06cc\u0634\u062a\u0631 \u0628\u0647\u200c\u062e\u0627\u0637\u0631 \u0646\u0642\u0634 \u0622\u0646 \u062f\u0631 \u062e\u0648\u0627\u0628 \u0634\u0646\u0627\u062e\u062a\u0647 \u0645\u06cc\u200c\u0634\u0648\u062f) \u0645\u06cc\u200c\u062a\u0648\u0627\u0646\u062f \u062f\u0631 \u062f\u0631\u0645\u0627\u0646 \u062e\u0648\u062f\u0650 \u0633\u0631\u0637\u0627\u0646 \u0646\u0642\u0634 \u062f\u0631\u0645\u0627\u0646\u06cc \u062f\u0627\u0634\u062a\u0647 \u0628\u0627\u0634\u062f \u06cc\u0627 \u062e\u06cc\u0631. \u062f\u0631 \u0627\u06cc\u0646 \u0628\u0631\u0631\u0633\u06cc\u060c \u0628\u0627 \u062a\u06a9\u06cc\u0647 \u0628\u0631 \u0645\u0631\u0648\u0631\u0647\u0627\u06cc \u0646\u0638\u0627\u0645\u200c\u0645\u0646\u062f\u060c \u06a9\u0627\u0631\u0622\u0632\u0645\u0627\u06cc\u06cc\u200c\u0647\u0627\u06cc \u062a\u0635\u0627\u062f\u0641\u06cc\u200c\u0633\u0627\u0632\u06cc\u200c\u0634\u062f\u0647 \u0648 \u0631\u0627\u0647\u0646\u0645\u0627\u0647\u0627\u06cc \u0628\u0627\u0644\u06cc\u0646\u06cc \u0645\u0639\u062a\u0628\u0631 \u062c\u0647\u0627\u0646\u06cc\u060c \u0634\u0648\u0627\u0647\u062f \u0631\u0627 \u0628\u0647\u200c\u0635\u0648\u0631\u062a \u062f\u0642\u06cc\u0642 \u0648\u0644\u06cc \u0642\u0627\u0628\u0644\u200c\u0641\u0647\u0645 \u0645\u0631\u0648\u0631 \u0645\u06cc\u200c\u06a9\u0646\u06cc\u0645 [&hellip;]<\/p>\n","protected":false},"author":4,"featured_media":3748,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[54,59,173,526],"tags":[113,143,548,547],"class_list":["post-3747","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-facts","category-drug-and-interventions","category-lifestyle","category-cochrane","tag-113","tag-143","tag-548","tag-547"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v24.9 (Yoast SEO v28.6) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>\u0631\u0627\u0633\u062a\u06cc\u200c\u0622\u0632\u0645\u0627\u06cc\u06cc: \u0645\u0644\u0627\u062a\u0648\u0646\u06cc\u0646 \u062f\u0631 \u062f\u0631\u0645\u0627\u0646 \u0633\u0631\u0637\u0627\u0646 \u0645\u0624\u062b\u0631 \u0627\u0633\u062a. - \u0641\u06a9\u062a \u0646\u0627\u0645\u0647 \u0633\u0644\u0627\u0645\u062a<\/title>\n<meta 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